porfiromycin [=N-methylmitomycin] - PMC

Result Filters

You searched 8+ million full text articles

Try this search in 34+ million citations and abstracts

PMC Full-Text Search Results

Items: 1 to 20 of 188

<< First< Prev

Page of 10

Next >Last >>

Unknown field was ignored: [=N-methylmitomycin].

Select item 402571.

Differential toxicity of mitomycin C and porfiromycin to aerobic and hypoxic Chinese hamster ovary cells overexpressing human NADPH:cytochrome c (P-450) reductase.

M F Belcourt, W F Hodnick, S Rockwell, A C Sartorelli

Proc Natl Acad Sci U S A. 1996 Jan 9; 93(1): 456–460. doi: 10.1073/pnas.93.1.456

PMCID:: PMC40257

Summary Page Browse PDF–1.0M

Select item 22470632.

Deficient activation by a human cell strain leads to mitomycin resistance under aerobic but not hypoxic conditions.

R. S. Marshall, M. C. Paterson, A. M. Rauth

Br J Cancer. 1989 Mar; 59(3): 341–346. doi: 10.1038/bjc.1989.67

PMCID:: PMC2247063

Summary Page Browse PDF–1.2M

Select item 179163.

Mitomycin resistance in mammalian cells expressing the bacterial mitomycin C resistance protein MCRA

Michael F. Belcourt, Philip G. Penketh, William F. Hodnick, David A. Johnson, David H. Sherman, Sara Rockwell, Alan C. Sartorelli

Proc Natl Acad Sci U S A. 1999 Aug 31; 96(18): 10489–10494. doi: 10.1073/pnas.96.18.10489

PMCID:: PMC17916

Article PDF–118K

Select item 107150164.

Screening the NCI diversity set V for anti-MRSA activity: cefoxitin synergy and LC-MS/MS confirmation of folate/thymidine biosynthesis inhibition

Shivani Gargvanshi, Gioia Heravi, Navid J. Ayon, William G. Gutheil

Microbiol Spectr. 2023 Nov-Dec; 11(6): e00541-23. Published online 2023 Oct 27. doi: 10.1128/spectrum.00541-23

PMCID:: PMC10715016

Article PDF–762K

Select item 45562265.

Validation of an HPLC-MS/MS and Wipe Procedure for Mitomycin C Contamination

C. B’Hymer, T.H. Connor, D. Stinson, J.R. Pretty

J Chromatogr Sci. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: J Chromatogr Sci. 2015 Apr; 53(4): 619–624. Published online 2014 Aug 16. doi: 10.1093/chromsci/bmu095

PMCID:: PMC4556226

Article PDF–325K

Select item 31400056.

Six Degrees of Separation: The Oxygen Effect in the Development of Radiosensitizers

Bryan T Oronsky, Susan J Knox, Jan Scicinski

Transl Oncol. 2011 Aug; 4(4): 189–198. Published online 2011 Aug 1. doi: 10.1593/tlo.11166

PMCID:: PMC3140005

Article PDF–281K

Select item 91792817.

Significance of Specific Oxidoreductases in the Design of Hypoxia-Activated Prodrugs and Fluorescent Turn off–on Probes for Hypoxia Imaging

Ewelina Janczy-Cempa, Olga Mazuryk, Agnieszka Kania, Małgorzata Brindell

Cancers (Basel) 2022 Jun; 14(11): 2686. Published online 2022 May 29. doi: 10.3390/cancers14112686

PMCID:: PMC9179281

Article PDF–2.8M

Select item 53792528.

DNA Adducts from Anticancer Drugs as Candidate Predictive Markers for Precision Medicine

Alessia Stornetta, Maike Zimmermann, George D. Cimino, Paul T. Henderson, Shana J. Sturla

Chem Res Toxicol. 2017 Jan 17; 30(1): 388–409. Published online 2016 Dec 12. doi: 10.1021/acs.chemrestox.6b00380

PMCID:: PMC5379252

Article PDF–2.4M

Select item 65354459.

Hypoxia-active nanoparticles used in tumor theranostic

Yaqin Wang, Wenting Shang, Meng Niu, Jie Tian, Ke Xu

Int J Nanomedicine. 2019; 14: 3705–3722. Published online 2019 May 22. doi: 10.2147/IJN.S196959

PMCID:: PMC6535445

Article PDF–2.3M

Select item 347420010.

Preliminary Studies with a New Hypoxia-Selective Cytotoxin, KS119W, In Vitro and In Vivo

Eugene Y. Kim, Yanfeng Liu, Oluwatoyin M. Akintujoye, Krishnamurthy Shyam, Tina A. Grove, Alan C. Sartorelli, Sara Rockwell

Radiat Res. Author manuscript; available in PMC 2013 Sep 1.

Published in final edited form as: Radiat Res. 2012 Sep; 178(3): 126–137. Published online 2012 Aug 3. doi: 10.1667/rr2934.1

PMCID:: PMC3474200

Article PDF–559K

Select item 366084511.

Preclinical Evaluation of Laromustine for use in Combination with Radiation Therapy in the Treatment of Solid Tumors

Sara Rockwell, Yanfeng Liu, Helen A. Seow, Kimiko Ishiguro, Raymond P. Baumann, Philip G. Penketh, Krishnamurthy Shyam, Oluwatoyin M. Akintujoye, Peter M. Glazer, Alan C. Sartorelli

Int J Radiat Biol. Author manuscript; available in PMC 2013 May 22.

Published in final edited form as: Int J Radiat Biol. 2012 Mar; 88(3): 277–285. Published online 2011 Dec 20. doi: 10.3109/09553002.2012.638359

PMCID:: PMC3660845

Article PDF–1.0M

Select item 386498812.

The Mitomycinoid Alkaloids: Mechanism of Action, Biosynthesis, Total Syntheses and Synthetic Approaches

Phillip D. Bass, Daniel A. Gubler, Ted C. Judd, Robert M. Williamsa

Chem Rev. Author manuscript; available in PMC 2014 Aug 14.

Published in final edited form as: Chem Rev. 2013 Aug 14; 113(8): 6816–6863. Published online 2013 May 8. doi: 10.1021/cr3001059

PMCID:: PMC3864988

Article PDF–9.9M

Select item 636170613.

Hypoxia-targeted drug delivery

Amit Sharma, Jonathan F. Arambula, Seyoung Koo, Rajesh Kumar, Hardev Singh, Jonathan L. Sessler, Jong Seung Kim

Chem Soc Rev. Author manuscript; available in PMC 2020 Feb 4.

Published in final edited form as: Chem Soc Rev. 2019 Feb 4; 48(3): 771–813. doi: 10.1039/c8cs00304a

PMCID:: PMC6361706

Article PDF–6.0M

Select item 388362114.

Expression of Human NAD(P)H:Quinone Oxidoreductase (DT-Diaphorase) in Chinese Hamster Ovary Cells: Effect on the Toxicity of Antitumor Quinones

DANIEL L. GUSTAFSON, HOWARD D. BEALL, EMIKO M. BOLTON, DAVID ROSS, CHARLES A. WALDREN

Mol Pharmacol. Author manuscript; available in PMC 2014 Jan 7.

Published in final edited form as: Mol Pharmacol. 1996 Oct; 50(4): 728–735.

PMCID:: PMC3883621

Article PDF–389K

Select item 351929115.

Convergent synthesis of a steroidal antiestrogen-mitomycin C hybrid using “click” chemistry

Robert N. Hanson, Edward Hua, David Labaree, Richard B. Hochberg, Kyle Proffitt, John M. Essigmann, Robert G. Croy

Org Biomol Chem. Author manuscript; available in PMC 2013 Nov 14.

Published in final edited form as: Org Biomol Chem. 2012 Nov 14; 10(42): 8501–8508. Published online 2012 Sep 25. doi: 10.1039/c2ob25902h

PMCID:: PMC3519291

Article PDF–654K

Select item 254771416.

On-line reductive cyclic voltammetric analysis of the anticancer agents mitomycin C, some of its degradation products and profiromycin

H. H. J. L. Ploegmakers, M. J. M. Mertens, W. J. van Oort

J Automat Chem. 1987; 9(4): 149–157. doi: 10.1155/S1463924687000312

PMCID:: PMC2547714

Summary PDF–1.2M

Select item 1021617117.

Targeting Hypoxia-Inducible Factor-1α for the Management of Hepatocellular Carcinoma

Kenneth N. Huynh, Sriram Rao, Bradley Roth, Theodore Bryan, Dayantha M. Fernando, Farshid Dayyani, David Imagawa, Nadine Abi-Jaoudeh

Cancers (Basel) 2023 May; 15(10): 2738. Published online 2023 May 12. doi: 10.3390/cancers15102738

PMCID:: PMC10216171

Article PDF–1.7M

Select item 870754818.

Restoring Tumour Selectivity of the Bioreductive Prodrug PR-104 by Developing an Analogue Resistant to Aerobic Metabolism by Human Aldo-Keto Reductase 1C3

Maria R. Abbattista, Amir Ashoorzadeh, Christopher P. Guise, Alexandra M. Mowday, Rituparna Mittra, Shevan Silva, Kevin O. Hicks, Matthew R. Bull, Victoria Jackson-Patel, Xiaojing Lin, Gareth A. Prosser, Neil K. Lambie, Gabi U. Dachs, David F. Ackerley, Jeff B. Smaill, Adam V. Patterson

Pharmaceuticals (Basel) 2021 Dec; 14(12): 1231. Published online 2021 Nov 26. doi: 10.3390/ph14121231